Our observation was that bromhidrosis patients reported slight elevated candida sp. levels in combination mit reduced enterococcus sp. in stool analysis results. The current metabolism impact for bromhidrosis seems to be sourced in a deficient acetate or propionate degrading enzyme which is part of the major ethanol degradation. The biosynthesis of ethanol is mostly based on candida sp., so we investigated into the pathogenesis of candida. The following pictures show the resulting disease model. In the case of an deficiency in the ethanol degradation pathway, the immune system shows a weakness regarding the candida sp., which shifts the microbiome towards increased candida occurence and activity. This would lead to small intestinal fungal overgrowth (SIFO) symptoms
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