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Candida pathogenesis in Bromhidrosis

Our observation was that bromhidrosis patients reported slight elevated candida sp. levels in combination mit reduced enterococcus sp. in stool analysis results.

The current metabolism impact for bromhidrosis seems to be sourced in a deficient acetate or propionate degrading enzyme which is part of the major ethanol degradation.

The biosynthesis of ethanol is mostly based on candida sp., so we investigated into the pathogenesis of candida.

The following pictures show the resulting disease model.

In the case of an deficiency in the ethanol degradation pathway, the immune system shows a weakness regarding the candida sp., which shifts the microbiome towards increased candida occurence and activity.

This would lead to small intestinal fungal overgrowth (SIFO) symptoms 

Comments

  1. Is this reversible condition? as in , enzyme supplements can reverse bromhidrosis ? or any other deductible course of treatment/management ?

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  2. Antifungals like nystatin show their effect after 3-4 weeks. Be aware, that it only lowers the body odor to a certain degree and mostly the propionate compound and not the other compounds necessarily.
    It seems to apply to one type of Bromhidrosis patients with elevated TSH and not necessarily to other bromhidrosis types.
    Other types with elevated PTH e.g. seem to react much better on calcium reduction and vitamine D reduction.
    Btw: there are fecal analysis tests available which show candida sp. distribution and elevated results in above cases. measure first if possible even if e.g. nystatin is a well known drug with only low side effects.


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    2. Do you wanna send me more details per mail?
      awonderland6( at )googlemail.com

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