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Diet, medicinal clay and large doses of a histamine-1 receptor blocker does reduce body odor in the bromhidrosis with elevated TSH type drastically

In an explorative case with strong sweaty body odor, normally associated with 'apocrine' bromhidrosis, the odor emission reduces drastically after two weeks of large doses of loratadin (>50mg daily)

During that period a diet was in place:
- exlusion of high histidine foods
- exclusion of sugar holding foods
- meals did contain only proteins or carbohydrates but no mixture of both

During that period following supplements were taken:
- Vitamine C (1000mg)
- Medicinal clay especially for histamine intolerance


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Candida pathogenesis in Bromhidrosis

Our observation was that bromhidrosis patients reported slight elevated candida sp. levels in combination mit reduced enterococcus sp. in stool analysis results.
The current metabolism impact for bromhidrosis seems to be sourced in a deficient acetate or propionate degrading enzyme which is part of the major ethanol degradation.
The biosynthesis of ethanol is mostly based on candida sp., so we investigated into the pathogenesis of candida.
The following pictures show the resulting disease model.
In the case of an deficiency in the ethanol degradation pathway, the immune system shows a weakness regarding the candida sp., which shifts the microbiome towards increased candida occurence and activity.
This would lead to small intestinal fungal overgrowth (SIFO) symptoms