As stated in an earlier post, the most prominent reported smell type for TMAU2 patients was the fecal smell type. But not only TMAU positive patients reported such a type of smell, another body odor sufferer type do show the same fecal body odor pattern. Interestingly nearly all of those non TMAU patients report having Irritable Bowel Syndrom (IBS) as well. We took a closer look into the combined bacterial and human metabolism. The central chemical compound involved in the fecal smell seems to be indole. Indole is produced within the bacterial metabolism as a precursor of tryptophan. As major source the bacteria use glycolysis based on sugar, carbohydrates, ... To let the bacteria produce too much indole we found certain criteria: - Tryptophan absorption of the intestinal cells is lower than the serine and glycine absorption - Histidine malabsorption is present - Tyrosine malabsorption is present Why do TMAU2 patients now show a fecal smell, don't they have a choline and
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